

The tragically inbred Spanish king whose feeble health and inability to produce an heir plunged Europe into a continent-wide war.
Charles II of Spain, known as "El Hechizado" (The Bewitched), was a monarch defined by his profound physical and mental infirmities, a living testament to the destructive consequences of Habsburg dynastic inbreeding. He ascended the throne at age four, with his mother acting as regent, but he was never fit to rule. Suffering from a host of genetic disorders likely including the 'Habsburg jaw' (mandibular prognathism) and intellectual disability, he was often ill and described as melancholic and weak. His two marriages failed to produce any living heirs, despite intense national prayers and the scrutiny of Europe. His court became a battleground for foreign ambassadors and domestic factions vying for influence over the clearly declining king and, more importantly, over the succession to the vast Spanish Empire. His death in 1700 was the final act of a long decline. By naming Philip of Anjou, a French Bourbon grandson of Louis XIV, as his heir, he directly triggered the War of the Spanish Succession, a massive conflict that redrew the map of Europe.
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He was the product of generations of uncle-niece and first-cousin marriages; his own parents were uncle and niece.
Contemporary rumors attributed his poor health to witchcraft, leading to his nickname 'The Bewitched.'
He did not speak until age four and could not walk until age eight, according to court reports.
An autopsy performed after his death noted his heart was "the size of a grain of pepper," his lungs corroded, and his intestines rotten.
He had only one functioning testicle, which was noted in a post-mortem examination, contributing to his infertility.
“God will give me heirs.”