

Christian de Duve discovered the lysosome in 1955, a membrane-bound organelle that functions as the cell's digestive system, and later identified the peroxisome. This work, which earned him a share of the 1974 Nobel Prize in Physiology or Medicine, fundamentally redrew the map of the cell's interior architecture. A common misunderstanding is that these were mere observational discoveries; in fact, de Duve's genius lay in his method of cell fractionation, a precise biochemical technique that separated cellular components by centrifugation for the first time. His findings provided the mechanistic basis for understanding a host of genetic storage diseases and the process of programmed cell death. De Duve's legacy endures in every modern textbook diagram of the cell and in ongoing research into cellular recycling and metabolic disorders.
1901–1927
Grew up during the Depression, fought World War II, and built the postwar economic boom. Defined by shared sacrifice, institutional trust, and a belief that hard work and loyalty would be rewarded.
Christian was born in 1917, placing them squarely in The Greatest Generation. The events that shaped this generation — world wars, depression, and rapid industrialization — shaped the world they entered and the choices available to them.
The biggest hits of 1917
#1 Movie
Cleopatra
The world at every milestone
Russian Revolution overthrows the tsar; US enters WWI
King Tut's tomb discovered in Egypt
Pluto discovered
FDR's New Deal launches; Prohibition ends
Social Security Act signed into law
Kristallnacht and the escalation toward WWII
India gains independence; the Dead Sea Scrolls found
Sputnik launches the Space Age
Summer of Love in San Francisco; first Super Bowl
Star Wars premieres; Elvis dies
Black Monday stock market crash
Princess Diana dies in Paris car crash; Harry Potter published
Edward Snowden reveals NSA surveillance programs
“Life is an obligatory chemical reaction, but it need not be a trivial one.”